Firefighters were called to reports of a fire at a property in Chirk at 01.35hrs in the early hours of this morning (Wednesday).
Three fire appliances from Chirk, Llangollen and Wrexham were mobilised to the bungalow on LodgeValleyPark.
Firefighters wearing breathing apparatus rescued a 65-year-old woman from the property.
She was transferred to hospital by ambulance following preliminary treatment at the scene by paramedics for severe smoke inhalation. Her condition is described as serious.
Firefighters used six sets of breathing apparatus and two hose reel jets in extinguishing the fire.
A dog, also rescued from the property, is in a serious condition and the RSPCA is being consulted.
The damage to the property is currently being assessed and the cause of the fire is under investigation.